The role of carbomer as pharmaceutical excipients CAS NO.9003-01-4

1. High daily output and fast delivery

Desheng has a professional production base and adopts imported production equipment. The daily output of Carbomer 980 can reach 3-5 tons, which can meet the needs of customers for large quantities of orders. Customers no longer have to worry about the delivery cycle.

2. Customized parameters

Desun Carbomer 980 needs better thickening performance and high viscosity, viscosity can be customized according to customer needs

3. Good after-sales service

Desheng provides good after-sales service and guarantees that if there is any quality problem, it will result in a return. If there are no special circumstances, all product shipping costs will be borne by the company.

4. High cost performance

Desheng is carrying out the annual ultimate discount event. Carbomer has a preferential price of 130 yuan/kg over 980 tons. The product quality is guaranteed. Free trial installation is available.

Carbomer is a good gel and thickener. It should be used in skin care products, shampoo, toothpaste and other daily cleaning products. In addition, it is often used as pharmaceutical excipient and is included in Pharmacopoeia, such as some external application, various medical gels, Carbomer Eye Drops and so on.

Carbomer is a kind of acrylic polymer, which is acid in itself. It is neutral to gel. It is basically inert. In fact, Carbomer itself does not have medicinal effect, nor does it have toxic or bactericidal effect. When used as pharmaceutical excipients, it is usually used as a dispersant, inhibitor, gel, carrier or medium for effective pharmaceutical ingredients.

Carbomer hydrogel

Lysozyme drugs can promote the healing of burn wounds, because lysozyme can dissolve and destroy the cell walls of fungi and bacteria, has bactericidal effect, and will not damage human cells (animal cells are not affected by the cell walls of fungi and bacteria), but there are many defects in the direct use of lysozyme. Here, Carbomer lysozyme hydrogel is used to illustrate the role of carbomer.

1. lysozyme can not directly achieve sustained release effect, it is a typical protein, the preparation of sustained-release preparation is very difficult, adding in carbomer hydrogel has slow release effect.

2. The stability of lysozyme is poor α The spiral structure tends to be unstable β With the change of folding structure, the stability becomes worse and worse, and carbomer can improve its stability.

3. Lysozyme is hemolytic, which is mainly due to its misfolding β Carbomer 940 can reduce the hemolytic effect of carbomer 940.

It can be seen from the above that carbomer has the effect of sustained release, can also improve the stability of some protein drugs and reduce some side effects of drugs. In addition, the thickening effect of carbomer gel can make some drugs more convenient to use, for example, Carbomer Eye Drops is not easy to flow like ordinary eye drops. Some oral drugs can also directly reach the affected area through carbomer as a carrier, with better efficacy.

In short, Carbomer as a pharmaceutical excipient has no pharmacodynamic effect, but it can improve the pharmacodynamic effect from all aspects. Desheng is a high polymer R & D and synthesis enterprise, which can provide polymer materials such as Carbomer, serum separation gel, etc.