Factors Affecting the Properties of Carbomer Gels CAS NO.9003-01-4

1. High daily output and fast delivery

Desheng has a professional production base and adopts imported production equipment. The daily output of Carbomer 980 can reach 3-5 tons, which can meet the needs of customers for large quantities of orders. Customers no longer have to worry about the delivery cycle.

2. Customized parameters

Desun Carbomer 980 needs better thickening performance and high viscosity, viscosity can be customized according to customer needs

3. Good after-sales service

Desheng provides good after-sales service and guarantees that if there is any quality problem, it will result in a return. If there are no special circumstances, all product shipping costs will be borne by the company.

4. High cost performance

Desheng is carrying out the annual ultimate discount event. Carbomer has a preferential price of 130 yuan/kg over 980 tons. The product quality is guaranteed. Free trial installation is available.

 Carbomer produced by Wuhan Xindesheng is white loose powder with strong hygroscopicity. Therefore, it must be stored in a dry place in a plastic bag. When we use carbomer, it is usually made into gel and added to daily chemicals or medical raw materials for use. What are the factors that affect the properties of carbomer gels
1. Carbomer gel properties are affected by pH value
Because carbomer polymers have a large number of free carboxyl groups, the pKa values ??are usually small. If the pH of the medium is less than 4, the carboxyl groups are rarely separated, and if the pH is greater than 4, the carboxyl groups begin to separate, the polymer dissolves, and the viscosity increases. The pH value of the medium also affects the adhesion of carbomer gels. When the pH value is lower than pKa, the binding ability of the gel is strong, and the adhesion will increase. At the same time, the ionic strength of the medium can change the sensitivity of the carbomer gel to pH value. When the ionic strength is high, the carbomer easily releases protons and its pKa value decreases, so it can be dissolved at a lower pH value.
2. Carbomer gel properties are affected by ionic strength
In some drugs, the effect of the drug on the pH and ionic strength of the medium around the gel cannot be ignored. The acidity of the drug also affects the properties of the gel, so the effect of acidic drugs is more pronounced.
3. Carbomer gel properties are affected by other excipients
The simultaneous use of polyvinylpyrrolidine and polyoxyethylene as auxiliary agents in carbomer gels can reduce the mucoadhesion of carbomer gels. This reduction is related to the concentration and molecular weight of coexisting excipients. The high concentration of excipients ( 5%) can greatly reduce the adhesion of carbomer gel, and if the concentration is reduced to 0.5%, the effect is small. Generally, the pH of the medium does not change this property of polyvinylpyrrole and polyoxyethylene. Magnesium stearate is hydrophobic and therefore also reduces the adhesion of carbomer gels.
The above is the detailed introduction of Hubei Xindesheng Material Technology Co., Ltd. on the factors that affect the properties of carbomer gel. 

Hubei Xindesheng MaterialTechnology Co., Ltd. is a manufacturer specializing in the production of raw materials for biochemical testing and detection reagents, including carbomer 940 , there are also Carbomer 980, the main production is the daily chemical level, the quality is guaranteed, welcome your consultation and understanding.